Researchers from Taiwan found that individuals with hepatitis B — a known risk factor for liver cancer — were less likely to develop liver cancer if they received daily aspirin therapy.
Lead investigator Dr. Teng‐Yu Lee — of the Department of Gastroenterology at Taichung Veterans General Hospital in Taiwan — and colleagues recently reported their findings at The Liver Meeting 2017, held by the American Association for the Study of Liver Diseases in Washington, D.C.
Hepatitis B is a liver infection caused by hepatitis B virus (HBV). It is estimated to affect around 257 million people across the globe, and in 2015, the infection was responsible for around 887,000 deaths worldwide.
In the United States, it is estimated that between 850,000 and 2.2 million people have chronic hepatitis B.
According to the Centers for Disease Control and Prevention (CDC), approximately 15–25 percent of those with chronic hepatitis B go on to develop severe liver conditions, such as liver cirrhosis
There are antiviral therapies that can help to reduce liver cancer risk in people with hepatitis B, but Dr. Lee and team note that these medications do not fully eradicate the risk.
What is more, they note that some people infected with HBV are not deemed suitable candidates for antiviral medications, so there is a need for alternative therapies that can reduce the risk of liver cancer for these patients.
Previous studies have indicated that aspirin can help to lower cancer risk, but few studies have investigated the effects of this drug against liver cancer.
“Therefore,” says Dr. Lee, “we conducted a large-scale cohort study to evaluate the association of aspirin therapy with HBV‐related liver cancer.”
or liver cancer. Each year, around 1,800 people in the U.S. die from HBV-related liver diseases.